What Is an Elevated PSA?
PSA is a protein produced by prostate tissue. A small amount normally circulates in the blood, and PSA levels often increase gradually as the prostate enlarges with age. There is no single PSA value that can determine by itself whether a man has prostate cancer.
An elevated PSA means that the result is higher than expected for the individual patient or has changed in a way that deserves further evaluation. In some cases, repeating the PSA after an appropriate interval is the first step. In others, additional testing such as a prostate examination, urine testing, prostate MRI, or other risk-assessment tools may be useful.
When a PSA is newly elevated, repeating the PSA before moving directly to a prostate MRI or biopsy is often appropriate. PSA can vary from one test to another, and temporary factors can affect the result.
The goal is not simply to lower the PSA. The goal is to understand why it is elevated and determine whether there is enough concern for clinically significant prostate cancer to justify additional testing or biopsy.
